LPC-37:副乾酪乳桿菌 紓壓護腦減焦慮

精簡版於2021年12月31日晴報刊登

益生菌能改善腸道、調節免疫力等功能大家都知。除了這些功效外，亦有部份益生菌有其他特別效用。例如前文介紹關於腸腦軸的情緒益生菌副乾酪乳桿菌 Lpc-37 (Lactobacillus paracasei Lpc-37 )，在動物實驗中亦發現有不少與腸腦軸相關的功效。

副乾酪乳桿菌LPC-37  配合輔助減感染

副乾酪乳桿菌 Lpc-37 (Lactobacillus paracasei Lpc-37 )是從奶品中發現的益生菌，它的基因圖譜、穩定性及安全性等都已通過測試，並在歐洲EFSA及美國FDA取得安全認證。多年來Lpc-37大多作為多元益生菌組合的其中一種，配合基本的調理腸道功能，及與其他益生菌相輔相成。例如在印度的研究中，Lpc-37配合HN019作為補充劑給學齡前兒童服用九個月後，他們因感染而發燒腹瀉的發病率都有所降低。

憂鬱焦慮壓力大    益生菌舒壓降皮質醇

近年有動物實驗以每天定時束縛小鼠令其有心理壓力及焦慮，再分別以益生菌或安慰劑餵飼。在測試焦慮行為的迷宮及礦野測試中，Lpc-37組別小鼠因束縛而出現的焦慮行為明顯改善至沒有束縛小鼠的水平。而在抑鬱及認知功能測試中，Lpc-37組別都有顯著的改善。因壓力而上升的「壓力賀爾蒙」皮質醇，在Lpc-37組別中亦能回復至沒有束縛小鼠的水平。另有實驗以剝奪小鼠的睡眠時間令其認知能力下降，再以Lpc-37益生菌或安慰劑餵飼。結果發現食用Lpc-37小鼠在認知行為測試中有顯著改善至正常水平。

副乾酪乳桿菌 Lpc-37 以動物實驗為基礎,證實其調控情緒賀爾蒙、舒緩壓力及與其他益生菌相輔相成的功效。新推出的益緒寧富含170億副乾酪乳桿菌 Lpc-37及聚葡萄糖(Polydextrose)益生元，有助調節腸腦軸、改善情緒等。而有關Lpc-37更多的臨床研究，敬請留意後續《益生第一關》再一一介紹。

參考資料/延伸閱讀:

＜益生第一關＞2021/12/17--『益生菌調理腸道 有助治療自閉症』

https://hskgene.com/blogs/probiolife-first/probiotics_and_autism

＜益生第一關＞2021/12/03 --『自閉症腸道相關 微生態有助改善』

https://hskgene.com/blogs/probiolife-first/autism

＜益生第一關＞2021/07/30 --『腸道大腦互影響 行為健康同維持』

https://hskgene.com/blogs/probiolife-first/gut-brain-axis-behavior

＜益生第一關＞2017/12/08---『腸道細菌影響大腦功能。大腦與第二大腦對話』

https://hskgene.com/blogs/probiolife-first/gut-brain-axis

＜益生第一關＞2016/06/09---『幸福從腸道開始』

https://skypost.ulifestyle.com.hk/article/1831979/%E5%B9%B8%E7%A6%8F%E5%BE%9E%E8%85%B8%E9%81%93%E9%96%8B%E5%A7%8B

＜益生第一關＞2018/05/25---『健康腸道菌 舒緩「腸易激」(二)』

https://hskgene.com/blogs/probiolife-first/irritable-bowel-syndrome-2

＜益生第一關＞2017/04/07--『健康腸道菌紓緩「腸易激」』

https://skypost.ulifestyle.com.hk/article/1765890/%E5%81%A5%E5%BA%B7%E8%85%B8%

Easy Reading:

皮質醇過高不只老得快！失智、糖尿病7大健康風險和它有關|早安健康|2019-11-22

https://www.edh.tw/article/22925

壓力過大恐讓５種疾病跟著來! | Heho健康 |2020-06-06

https://today.line.me/tw/v2/article/nyppWo

The Gut-Brain Connection: How it Works and The Role of Nutrition| Healthline|08-20-2020

https://www.healthline.com/nutrition/gut-brain-connection#TOC_TITLE_HDR_5

Is Anxiety Making You Poop? Here’s How to Soothe Your Stomach|Healthline|03-09-2021

https://www.healthline.com/health/mental-health/is-anxiety-making-you-poop-heres-how-to-soothe

Stress, not diet, likely source of GI problems in children with autism|Healio| 07-14-2017

https://www.healio.com/news/gastroenterology/20170713/stress-not-diet-likely-source-of-gi-problems-in-children-with-autism

Dopamine and Parkinson's disease: What to know| Medical News Today| 06-01-2021

https://www.medicalnewstoday.com/articles/dopamine-parkinsons

Google images:

IBS autism  IBS cortisol  Parkinson's disease Dopamine

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